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There are also rare adverse reactions like angina pectoris, coronary artery disease, cardiac arrhythmia, cerebral ischemia, cerebrovascular lesion, heart block, peripheral cyanosis, thrombosis, short-lived myocardial ischemia, and vasodilation or dilation of blood vessels (especially the arteries) A number of side effects may occur that usually do not need medical consideration.
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03 Nov 09 Adverse Reactions of generic Imitrex Sumatriptan part 3

There are also rare adverse reactions like angina pectoris, coronary artery disease, cardiac arrhythmia, cerebral ischemia, cerebrovascular lesion, heart block, peripheral cyanosis, thrombosis, short-lived myocardial ischemia, and vasodilation or dilation of blood vessels (especially the arteries)

A number of side effects may occur that usually do not need medical consideration. It is noticed that some of the effects, such as drowsiness, nausea, vomiting, dizziness, and general feeling of illness or tiredness, often come about during or after a migraine, even in the lack of usage of sumatriptan. Nearly all of the side effects caused by sumatriptan (Japanese name スマトリプタン ) move within a short time (less than 1 hour after an injection or 2 hours after a tablet). Yet, consult your doctor if any of the following side effects continue or are bothersome:

Numerous endocrine and metabolic diseases include thirstiness, hypoglycemia; hypothyroidism or glandular disorder ; elevated thyrotropic hormone stimulating hormone (TSH) levels; galactorrhea; hyperglycemia (abnormally high blood sugar usually associated with diabetes); polydipsia or excessive thirst; weight gain; weight loss; endocrine cysts, lumps, and masses; and fluid disturbances.

There are some gastrointestinal diseases caused by this drug. These are diarrhea and gastric symptoms. Some uncommon adverse reactions are dysphagia, constipation, and gastroesophageal reflux. There are also exceptional disease like hypersalivation, abdominal distention, peptic ulcer, gastrointestinal bleeding, hematemesis, melena, gastrointestinal pain, dyspeptic symptoms, dental pain, feelings of gastrointestinal pressure, gastroesophageal reflux, gastritis, gastroenteritis, oral itching and irritation, salivary gland swelling, and swallowing disorders.

Myalgia is a common side effect of generic Imitrex. It also occasionally causes arthralgia and articular rheumatitis; muscle cramps, tetany; muscle atrophy, weakness, and tiredness; acquired musculoskeletal deformity; muscle stiffness, tightness, and rigidity; and musculoskeletal inflammation.

Serious cardiac events have been reported by some patients using Imitrex tablets. These events are generally exceptional. Some patients suffer from transient myocardial ischemia, coronary artery vasospasm, myocardial infarction, ventricular tachycardia, and ventricular fibrillation by using this drug.